530-752-6364

Principal Investigator: Dr. Carlito Lebrilla Email: cblebrilla@ucdavis.edu

2025

Stejskalova, A.; Calderon, K.; Chou, D. B.; Gulati, A.; Feitor, J. F.; Izadifar, Z.; Gutzeit, O.; Bouchibti, Y.; Chen, S.; Plebani, R.; Cotton, J.; Hughes, J.; Ferrante, T.; Budnik, B.; Goyal, G.; Junaid, A.; Lebrilla, C. B.; Ingber, D. E. Induction of cervical dysfunction associated with preterm birth by IL-1 and dysbiotic microbiome revealed in human endocervix chips. bioRxiv 2025, preprint. https://doi.org/10.1101/2025.05.01.651107.

Ophir, Y.; Wong, J.; Haddad, K. R.; Huuskonen, A.; Karmaker, A.; Gore, V.; Jung, S.; Oloumi, A.; Liu, Y.; Fu, J.; Zhang, L.; Huang, P.; Minami, S. A.; Garimella, S. S.; Thyagatur, A.; Zaini, P. A.; Vitikainen, M.; Tchelet, R.; Valbuena, N.; Fuerst, T. R.; Korkmaz, E.; Falo, L. D., Jr.; Balmert, S. C.; Mahendiratta, S.; Emalfarb, M.; Shah, P. S.; Siegel, J.; Dandekar, A. M.; Chen, X.; Lebrilla, C.; Faller, R.; Saloheimo, M.; McDonald, K. A.; Nandi, S. Expression and Characterization of SARS-CoV-2 Spike Protein in Thermothelomyces heterothallica C1. bioRxiv 2025, preprint. https://doi.org/10.1101/2025.05.01.651343.

Tang, X.; Schindler, R. L.; Di Lucente, J.; Oloumi, A.; Tena, J.; Harvey, D.; Lebrilla, C. B.; Zivkovic, A. M.; Jin, L.-W.; Maezawa, I. Unique N-Glycosylation Signatures in Human iPSC Derived Microglia Activated by Aβ Oligomer and Lipopolysaccharide. Sci. Rep. 2025, 15, 12348. https://doi.org/10.1038/s41598-025-19380-0.

Tang, R. L.; Jin, L.-W.; Zivkovic, A. M.; Liu, Y.; Lebrilla, C. B. Region‑Specific Quantitation of Glycosphingolipids in the Elderly Human Brain with Nanoflow MEA Chip Q/ToF Mass Spectrometry. Glycobiology 2025, 35 (6), cwaf022. https://doi.org/10.1093/glycob/cwaf022

Alvarez, M. R. S.; Holmes, X. A.; Oloumi, A.; Grijaldo‑Alvarez, S. J.; Schindler, R.; Zhou, Q.; Yadlapati, A.; Silsirivanit, A.; Lebrilla, C. B. Integration of RNAseq Transcriptomics and N‑Glycomics Reveal Biosynthetic Pathways and Predict Structure‑Specific N‑Glycan Expression. Chem. Sci. 2025, 16, 7155–7172. https://doi.org/10.1039/D5SC00467E

Masarweh, C.; Maldonado‑Gomez, M.; Paviani, B.; Bhattacharya, M.; Weng, C.-Y.; Suarez, C.; Ehlers‑Cheang, S.; Stacy, A.; Castillo, J.; Krishnakumar, N.; Kalanetra, K. A.; Barile, D.; German, J. B.; Lebrilla, C. B.; Mills, D. A. Generation of Novel Prebiotic Oligosaccharide Pools from Fiber Drives Biological Insight in Bacterial Glycan Metabolism. Appl. Environ. Microbiol. 2025, 91 (3), e02077‑24. https://doi.org/10.1128/aem.02077‑24.

Silsirivanit, A.; Alvarez, M. R. S.; Grijaldo‑Alvarez, S. J.; Gogte, R.; Kitkhuandee, A.; Piyawattanametha, N.; Seubwai, W.; Luang, S.; Panawan, O.; Mahalapbutr, P.; Vaeteewoottacharn, K.; Sawanyawisuth, K.; Let‑itthiporn, W.; Saengboonmee, C.; Duangthongphon, P.; Jingjit, K.; Pankongsap, A.; Waraasawapati, S.; Aphivatanasiri, C.; Lebrilla, C. B. Serum N‑Glycomics with Nano‑LC‑QToF LC‑MS/MS Reveals N‑Glycan Biomarkers for Glioblastoma, Meningioma, and High‑Grade Meningioma. J. Proteome Res. 2025, 24 (3), 1402–1413. https://doi.org/10.1021/acs.jproteome.4c01090.

Suarez, C.; Ehlers Cheang, S.; Larke, J. A.; Jiang, J.; Weng, C.-Y. C.; Stacy, A.; Couture, G.; Chen, Y.; Bacalzo, N. P.; Smilowitz, J. T.; German, J. B.; Mills, D. A.; Lemay, D. G.; Lebrilla, C. B. Development of a Comprehensive Food Glycomic Database and Its Application: Associations between Dietary Carbohydrates and Insulin Resistance. Food Chem. 2025, 473, 142977. https://doi.org/10.1016/j.foodchem.2025.142977.

Chen, S.; Xie, Y.; Alvarez, M. R.; Sheng, Y.; Bouchibti, Y.; Chang, V.; Lebrilla, C. B. Quantitative Glycan-Protein Cross-Linking Mass Spectrometry Using Enrichable Linkers Reveals Extensive Glycan-Mediated Protein Interaction Networks. Anal. Chem. 2025, 97 (3), 1584–1593. https://doi.org/10.1021/acs.analchem.4c04134.

Tang, X.; Schindler, R.; Lucente, J.; Oloumi, A.; Tena, J.; Harvey, D.; Lebrilla, C.; Zivkovic, A.; Jin, L.-W.; Maezawa, I. Unique N-Glycosylation Signatures in Aβ Oligomer- and Lipopolysaccharide-Activated Human iPSC-Derived Microglia. Sci. Rep. 2025, 15, 12348. https://doi.org/10.1038/s41598-025-12348. PMCID: PMC11601871, PMID: 39606433.

Suarez, C.; Ehlers Cheang, S.; Larke, J. A.; Jiang, J.; Weng, C.-Y. C.; Stacy, A.; Couture, G.; Chen, Y.; Bacalzo, N. P., Jr.; Smilowitz, J. T.; German, J. B.; Mills, D. A.; Lemay, D. G.; Lebrilla, C. B. Development of a Comprehensive Food Glycomic Database and Its Application: Associations between Dietary Carbohydrates and Insulin Resistance. Food Chem. 2025, 473, 142977. https://doi.org/10.1016/j.foodchem.2025.142977.